Abstract
Young rats were given two doses of 50 mg 5-fluorouracil with a 22-hour interval. One hour after the second dose they were given either cytidine-3H or leucine-3H and killed three hours later. Radioautographs of the livers revealed a decrease in RNA labelling, whereas the protein labelling was essentially uninfluenced. The liver cells exhibited an increase in nucleolar volume. Electron microscopy revealed changes in the ultrastructure of the liver cell nucleoli, while other parts of the cells were essentially unaltered.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Zeitschrift f�r Zellforschung und Mikroskopische Anatomie
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
