Abstract
Cytokine Antibody Arrays: A Useful Tool in Biotechnology for the Screening of Specific Biomarkers in Eyes Diseases
Highlights
Antibody arrays is a recently established proteomic technology providing unique opportunities for various applications, such as protein expression profiling, biomarker discovery, disease diagnostics, prognostics, evidence-based therapy selection, and disease monitoring [1]
One of the advantages of antibody array technology is its capability of profiling proteins in non-fractionated biological samples
One array membrane was only incubated with lyses buffer. Another array membrane was incubated with a tear sample
Summary
Antibody arrays is a recently established proteomic technology providing unique opportunities for various applications, such as protein expression profiling, biomarker discovery, disease diagnostics, prognostics, evidence-based therapy selection, and disease monitoring [1]. One of the advantages of antibody array technology is its capability of profiling proteins in non-fractionated biological samples. As one of the most exciting emerging technologies, protein array provides a versatile and robust platform in cancer proteomics research because it shows tremendous advantages of miniaturized features, high throughput, and sensitive detections in last decades. Several studies are currently using protein array technologies for biomarker discovery in diseases like lupus and cancer [5,6]. The early diagnosis in very important in order to prevent several ocular damage and the decrease of the visual acuity and other permanent consequences [7], because there are important biochemical changes in the composition of the tear than usually appear before the patient be able to note any symptom [8]
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