Abstract

The most common brain tumors in children are neuroblastomas, whereas gliomas predominate in adults. Both tumours are known for their aggressive proliferation and diffuse invasive potential. The survival rate for patients with gliomas is less than 50%. However, the prognosis of individual cases with these brain tumours is highly variable and associated with a vast number of biological and clinical features. For example, the mortality in children with stage II and IV, younger than 12 months and with amplification of N-MYC gene exceeds 60%, while almost 100% of children in stage IVS, older than 12 months survive even without treatment.

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