Abstract

SummaryTwo children who presented a picture of unusually intense vomiting attacks accompanied by pronounced mental changes axe reported. During attacks the EEG was grossly abnormal only to become normal within a few days following the end of the attack. I n one case abnormalities of the EEG could be traced 10 days before the onset of a new vomiting period. A hesaniethonium bromide preparation tested in both children gave definite symptomatic relief but had no influence on the duration of the attack as a whole. This seemed to be the case, however, with chlorproniazine therapy. Autopsy in one child dying in an attack showed vascular changes of the teleangiectasia type with main localization in the left hippocampal region and in the pons; in the former region in combination with glious scar formation.

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