Abstract

AbstractPrecise deuterium labeling has gained significant attentions owing to the wide applications in organic synthesis, medicinal chemistry, and organic materials. C−C and C‐heteroatom bonds constitute the skeleton of organic molecules. This review summarizes the advancements on C−C and C‐heteroatom bond deuterations as well as their applications in late‐stage deuterations of natural products and pharmaceutically relevant molecules.

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