Abstract
OBJECTIVE: Oxidative stress caused by the imbalance between reactive oxygen species (ROS) and biological antioxidant system can lead to modification of DNA, lipid and proteins. Oxidative stress increases with aging. Copper/zinc superoxidant dismutase (CuZn-SOD) is one of the major antioxidant enzymes and localized in cytoplasm to scavenge superoxide. In addition, luteal dysfunction with aging is important clinical problem as to infertility.
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