Abstract
BackgroundCutaneous metastases in the facial region occur in less than 0.5% of patients with metastatic cancer.Case presentationA 52-year-old woman who admitted with a lung and a skull skin nodule is presented. She had a known diagnosis of uterine leiomyosarcoma following an extended total hysterectomy two years ago. Excision biopsy of both nodules revealed metastatic disease.ConclusionThe appearance of a cutaneous nodule in a patient with a history of uterine leiomyosarcoma might indicate a metastatic tumor lesion. Biopsy and immunohistochemistry are essential for correct diagnosis.
Highlights
Cutaneous metastases in the facial region occur in less than 0.5% of patients with metastatic cancer.Case presentation: A 52-year-old woman who admitted with a lung and a skull skin nodule is presented
Uterine leiomyosarcoma should be distinguished from benign uterine metastasizing leiomyoma which is diagnosed several years after myomectomy or hysterectomy with most commonly radiographic appearance of slowgrowing solitary or multiple lung nodules
In this report we describe an unusual case of uterine leiomyosarcoma metastasizing to the skull skin
Summary
Cutaneous metastases in the facial region occur in less than 0.5% of patients with metastatic cancer.Case presentation: A 52-year-old woman who admitted with a lung and a skull skin nodule is presented. Leiomyosarcoma is a rare malignant neoplasm composed of cells demonstrating smooth muscle differentiation. Uterine leiomysarcoma accounts for 25–36% of uterine sarcoma and 1% of all malignancies and has a poor prognosis due to a high metastatic recurrence rate. The commonly reported sites of metastasis from leiomysarcoma are the lung, kidney and liver [2].
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