Abstract

The skin is a window to systemic disease and malignancies, as it is readily visible. Cutaneous manifestations of internal malignancies include metastases to the skin, paraneoplastic dermatoses, malignancy associated genodermatoses, and dermatoses induced by environmental carcinogens. This article deals with the recognition and diagnosis of paraneoplastic dermatoses. doi:10.4038/cmj.v53i4.289 Ceylon Medical Journal Vol. 53, No. 4, December 2008 144-148

Highlights

  • Paraneoplastic dermatoses are important cutaneous markers of internal malignancy. They form a heterogeneous group of skin conditions, where tumour induced immunological factors, hormones, metabolic disorders, and epidermal growth factors may play a role in their genesis, and frequently indicate the type, localisation and prognosis of the underlying tumour

  • The course of the tumour and that of the skin manifestation generally run in parallel .When the skin condition and the neoplasm follow a parallel course, the former can be useful in monitoring recurrences of the latter

  • Paraneoplastic dermatoses are classified into those associated with solid tumours and those more commonly associated with haematological malignancies

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Summary

Cutaneous manifestations of neoplastic disease

The skin is a window to systemic disease and malignancies, as it is readily visible. Cutaneous manifestations of internal malignancies include metastases to the skin, paraneoplastic dermatoses, malignancy associated genodermatoses, and dermatoses induced by environmental carcinogens. This article deals with the recognition and diagnosis of paraneoplastic dermatoses

Paraneoplastic dermatoses
Acanthosis nigricans
Erythema gyratum repens
Multicentric reticulohistiocytosis
Acquired hypertrichosis languinosa
Acquired icthyosis
Sweet syndrome
Pyoderma gangrenosum
Paraneoplastic pemphigus
Cutaneous amyloidosis
Necrobiotic xanthogranuloma
Findings
Further reading
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