Abstract

Diosgenin (DG) is a naturally occurring steroid saponin that can be obtained from several plants. A lot of the artificial steroidal drugs that are used extensively in the pharmaceutical industry come from diosgenin for the treatment of various disease conditions. DG has various intriguing pharmacological effects, including anticancer, antidepressant, and anti-inflammatory and anti-infectious capabilities. Apart from its health advantages, DG is challenging to utilize in therapeutic applications due to its poor water solubility, bioavailability, and rapid physiological change. The DG nanotechnology for medicine formulations has been tested as a possible therapy for a variety of disorders employing a broad range of ex-vivo, in-vitro, and in-vivo models and delivery methods. Based on this analysis, it is possible to infer that DG is a viable therapeutic alternative for the management of numerous ailments, such as diabetes, cancer, neurological conditions, inflammatory diseases, and skin conditions.

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