Abstract
Type Ⅰ allergy is one type of allergic reaction mediated by IgE antibody. Simple, rapid and accurate allergen detection method can be used to identify the allergen of patients, which is of great significance for the prevention, diagnosis and treatment of allergic diseases. In this article, different techniques for in vitro diagnosis of allergen specific IgE antibodies in type Ⅰ allergic reactions were described, important factors affecting in vitro diagnosis of allergens were analyzed, and the future development trend of in vitro diagnosis of allergen specific IgE antibodies were prospected. In order to help clinicians to select more suitable in vitro detection methods in the process of in vitro diagnosis of type Ⅰ allergy and to better understand the internal relationship between the allergen specific IgE detection report and clinical symptoms.(Chin J Lab Med, 2018, 41: 889-892) Key words: Type I allergy; Allergens; Immunoglobulin E; in vitro diagnosis
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