Current notions about etiopathogenic and genetics specific features of &lt;i&gt;Сlostridium perfringens&lt;/i&gt; toxins

Yu V Lobzin,L I Zhelezova,A S Kvetnaya,N V Skripchenko

doi:10.36233/0372-9311-37

Abstract

The review presents modern data on the genetics and etiopathogenetic features of Clostridium perfringens toxins, including the role of Clostridium perfringens enterotoxin, in the development of food poisoning and a number of intestinal diseases in humans, animals and birds.

Highlights

Clostridium perfringens (СP), ранее известный как Bacillus aerogenes capsulatus, Bacillus perfrin gens, Bacillus welchii или Clostridium welchii, является грамположительной, спорообразующей, ан аэробной палочковидной бактерией [1]
Smithee L., McClane B., Distefano R.F., Uzal F., Songer J.G., Mallonee S., et al Fatal necrotizing colitis following a foodborne outbreak of enterotoxigenic Clostridium perfringens type A infection
Kiu R., Brown J., Bedwell H., Leclaire1 C., et al Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis

Summary

СПИСОК ИСТОЧНИКОВ

Sakurai J., Duncan C.L. Some properties of the beta-toxin produced by Clostridium perfringens type C. Robertson S.L., Li J., Uzal F.A., McClane B.A. Evidence for a prepore stage in the action of Clostridium perfringens epsilon toxin. Li J., Sayeed S., Robertson S., Chen J., McClane B.A. Sialidases affect the host cell adherence and epsilon toxin-induced cytotoxicity of Clostridium perfringens type D train CN3718. Smithee L., McClane B., Distefano R.F., Uzal F., Songer J.G., Mallonee S., et al Fatal necrotizing colitis following a foodborne outbreak of enterotoxigenic Clostridium perfringens type A infection. Microbiol Mol Biol Rev. 2013; 77(2): 208–233. Kiu R., Brown J., Bedwell H., Leclaire C., et al Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis.

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