Abstract

Since its first description in 1968 (1) alpha chain disease (α CD) has been recognized in 59 patients to our knowledge. Most of these cases have been detected or confirmed in our laboratory. Thus α CD is probably the most frequent disorder among the group of heavy chain diseases which, at present, includes diseases of the γ, α and μ types.KeywordsHinge RegionPathological ProteinReticulum Cell SarcomaHeavy Chain DiseaseIndependent Genetic ControlThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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