Abstract
Endocarditis is a relatively common and frequently devastating complication of cardiac valve replacement. Prosthetic valve endocarditis (PVE) has an overall yearly incidence ranging from about 1 to 4 percent of prostheses recipients.1–4 Previously, PVE has been arbitrarily divided into “early” and “late,” based on whether the infection occurred within 60 days of valve replacement or later.4 The rationale for this time categorization was based on differing bacteriologic, pathogenetic, and prognostic associations for PVE cases acquired before vs after this 60-day breakpoint.
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