Abstract
Osteoarthritis (OA) is currently considered as a heterogeneous disease that can be represented by different subtypes. It is the study of OA phenotypes that is one of the strategic areas for the development of researches on this nosological entity, which will further allow a personified approach to patient therapy and ensure the rational use of financial resources of health care.The paper describes in detail the current researches on this issue. It discusses attempts to identify different OA types according to demographic data (age, race, gender, etc.), comorbidity (including depression), nature of pain (intensity, pathophysiological mechanisms of its development), biochemical markers, genetic and biomechanical predictors, hormonal status in patients, and structural changes detected by ultrasound, magnetic resonance imaging, and computed tomography, etc.
Highlights
Osteoarthritis (OA) is currently considered as a heterogeneous disease that can be represented by different subtypes
It is the study of OA phenotypes that is one of the strategic areas for the development of researches on this nosological entity, which will further allow a personified approach to patient therapy and ensure the rational use of financial resources of health care
The paper describes in detail the current researches on this issue
Summary
Osteoarthritis (OA) is currently considered as a heterogeneous disease that can be represented by different subtypes It is the study of OA phenotypes that is one of the strategic areas for the development of researches on this nosological entity, which will further allow a personified approach to patient therapy and ensure the rational use of financial resources of health care. Группа ученых под руководством профессора K.E. Keuttner [1], созданная для изучения проблемы остеоартроза, подчеркивала патогенетическую гетерогенность болезни, а также видение ее как органной патологии, т. Понимания остеоартроза как дегенеративного процесса, ча- тов в зависимости от преобладающих патофизиологических сто связанного с возрастом, до рассмотрения его как воспа- изменений, не только для индивидуального подбора тералительной болезни (остеоартрит, ОА).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
