Abstract
Gastric cancer is the fourth most common type of cancer worldwide and the second most lethal. Gastric cancerbiomarkers can be used for diagnosis, prediction of sensitivity to treatment, and prognosis. The following search terms were applied to PubMed as of December 2020: 'gastric cancer classification', 'gastric cancer epidemiology', 'cancer metastasis'and 'gastric cancer biomarker'. Only experimental studies were reported in the 'biomarkers'section. Some biomarkers can serve as therapeutic targetsfor antitumoral drugs. The genes analyzed include E-cadherin, RPRM, XAF1, MINT25, TFF1, p16 and p53. The miRNAs analyzed include miR-18a, miR185-5p, miR-125b and miR-21. Some molecules were associated with metastasis of gastric cancer, specifically those involved with EMT process and tissue degradation.
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