Current Advances in the Diagnosis and Treatment of Sickle Cell Anaemia

Abstract

Sickle cell anemia (SCA) presents a complex challenge globally due to its significant morbidity and mortality. Recent advancements in diagnostic tools and treatment modalities have revolutionized the management of this hereditary hemoglobin disorder. This paper aims to synthesize current breakthroughs in the diagnosis and treatment of sickle cell anemia. Diagnostic techniques including genetic testing, hemoglobin electrophoresis, and advanced imaging methodologies are explored, providing insights into their accuracy and clinical applicability. Moreover, novel therapeutic approaches such as gene editing, fetal hemoglobin induction, and targeted therapies are discussed for their potential in ameliorating SCA-related complications and improving patient outcomes. The paper also assesses the challenges and future prospects in the field, emphasizing the need for comprehensive strategies that encompass early detection, personalized interventions, and ongoing research efforts. Understanding these recent strides in both diagnostics and therapeutics is pivotal in enhancing the care and prognosis of individuals afflicted with sickle cell anemia. Keywords: sickle cell anaemia, anaemia, treatment, diagnosis