Abstract
A new depsidone, curdepsidone A (1), was isolated form the culture extracts of curvularia sp. IFB-Z10, a white croaker associated fungus. The structure of 1 was elucidated on the basis of extensive spectroscopic analyses (HRESIMS, 1D and 2D NMR). Compound 1 showed significant cytotoxicity against human hepatoma cell lines BEL7402 and BEL7402/5- FU with IC50 values of 9.85 μM and 2.46 μM, respectively.
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