Curcuma longa tuber extract mediated synthesis of hydroxyapatite nanorods using biowaste as a calcium source for the treatment of bone infections

Abstract

Bone fillers based on hydroxyapatite (HAp) having antimicrobial activity are extensively applied for treatment of bone-related inflammation created by infectious micro-organisms. We report the biogenic preparation of HAp nanorods with the aid of Curcuma longa tuber extract as solvent and eggshell biowaste as a calcium source. The prepared powder was analyzed by various analytical tools to explore the phase purity and morphological feature. The obtained results indicate that the prepared powder was magnesium (Mg) and carbonate (CO32−) containing HAp nanorods having nanocrystalline characteristics. Further, the prepared HAp nanorods significantly hinder the growth of E. coli and S. aureus. Comparative studies were also carried out with HAp prepared using water as solvent. The obtained results clearly shows that developed method can be a prospective approach to acquire precursor material for making bone fillers with antibacterial activity.