Abstract
AbstractThe present investigation sought the use of Bovine Kidney Cells (BKC) which is a readily available substrate for the cultivation and isolation of measles virus. Results showed that measles virus grew well on BKC, showing identical cytopathologic effect (CPE) of syncytial and giant cell formation also noted for Vero cells. However, the growth on Vero cells was faster indicating a better sensitivity to the measles virus than BKC. The virus replicated and produced CPE in both confluent monolayer and trypsin dispersed cultures. The ability of the virus to form CPE was faster in trypsin‐dispersed cells than confluent monolayers.The viral yield in Vero‐ and BK‐cells were compared to assess any difference by analysis of variance. The F‐value of 0.824 with degree of freedom 1.34 showed no significant difference at any reasonable confidence interval.
Published Version
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