Abstract
This study focused on the application value of CT images of patients with organophosphorus poisoning lung injury. Specifically, 50 patients diagnosed with organophosphorus pesticide poisoning lung injury in the hospital were selected as research subjects. They all had chest CT examinations. Patients were classified according to different degrees of poisoning, and different groups were compared for the levels of C-reactive protein (CRP) and procalcitonin (PCT) in the serum. The results showed that, of the 50 patients, 25 patients had mild organophosphorus poisoning, accounting for 50%, 14 patients had moderate poisoning, accounting for 28%, and 11 patients suffered from severe organophosphorus poisoning. It was found that, in AOPP patients, cascade effect was exerted by stimulating the secretion of inflammatory mediators such as CRP, causing systemic inflammatory response syndrome, and multiorgan failure appeared in the early stage of the disease. After the histogram equalization treatment, the image was clearer than that processed by the other three methods. In terms of CT image smoothing, the effect of the Gaussian filtering was better than the mean filtering effect, and the effect of the median filtering was better than that of the Gaussian filtering. Therefore, the structure of the lungs became clearer, and the lung texture was also clearly displayed, and CT images after histogram equalization have an important value in the diagnosis of lung injury caused by organophosphorus poisoning.
Highlights
Because people do not use a mask to cover their mouth, nose, and skin when using organophosphorus pesticides, it is easy for the pesticides to enter the human body and eventually poison people [3]. e mechanism of acute organophosphorus poisoning (AOPP) is mainly related to acetylcholinesterase (AChE)
According to different AOPP groups and control groups, 2 ml of venous blood was collected within 2 h after admission, and serum hypersensitive C-reactive protein (CRP) concentration was determined by immunoturbidimetry
It has been found that, in AOPP patients, cascade effect is exerted by stimulating the secretion of inflammatory mediators such as CRP, causing systemic inflammatory response syndrome, and multiorgan failure appears in the early stage of the disease [18]
Summary
In all poisoning cases that occur each year, acute organophosphorus poisoning (AOPP) accounts for 1/5–1/2, and the fatality rate of patients after poisoning is as high as 40% [1, 2]. Organophosphorus is mainly used in agriculture and has insecticidal effects. Because people do not use a mask to cover their mouth, nose, and skin when using organophosphorus pesticides, it is easy for the pesticides to enter the human body and eventually poison people [3]. E mechanism of AOPP is mainly related to acetylcholinesterase (AChE). Organophosphorus pesticides can reduce the activity of AChE [4]. Studies have shown that the secretion of inflammatory mediators such as C-reactive protein (CRP)
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