Abstract
Background: Extramural venous invasion (EMVI) is a well-known poor prognostic factor, but only a subset of patients developed cancer recurrence. Considering major role of EMVI, we perceived two different types of EMVI: CT-diagnosed EMVI (ctEMVI, based on vascular enlargement with tumor density in CT scan) and pathologic EMVI (pEMVI, based on existing tumor cells in vein). We hypothesized that ctEMVI shows a tumor-host interaction during cancer dissemination and represents late-stage EMVI, while pEMVI represents early-stage EMVI. However, little is concerns about this difference. We aimed to assess whether ctEMVI and pEMVI have different prognostic implications and compare these to other known prognostic factors in colon cancer patients.
Published Version
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