Abstract

The relative contribution of CSF malabsorption and obstruction in three different etiological groups of neonatal high-pressure hydrocephalus (HC) was assessed in a study at University of Bonn, Germany, and University of Groningen, The Netherlands.

Highlights

  • Total body bone mineral density (TBBMD) was measured by X-ray absorptiometry in 46 brain tumor patients aged from 3.8 to 28.7 years at a mean of 6.4 y after end of treatment for brain tumor

  • TGF B-l concentrations were significantly higher in post-hemorrhagic HC cases than in SB HC and non-hemorrhagic HC; p=0.01 and 0.03, respectively

  • Median CSF PC1NP concentrations were significantly lower in SB HC (180 ng/ml) than in post-hemorrhagic HC (1,060 ng/ml); p=0.002

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Summary

Introduction

Total body bone mineral density (TBBMD) was measured by X-ray absorptiometry in 46 brain tumor patients aged from 3.8 to 28.7 years (mean 14.9 y) at a mean of 6.4 y (range 1.4-14.8 y) after end of treatment for brain tumor. CSF OBSTRUCTION AND MALABSORPTION IN CONGENITAL HYDROCEPHALUS The relative contribution of CSF malabsorption and obstruction in three different etiological groups of neonatal high-pressure hydrocephalus (HC) was assessed in a study at University of Bonn, Germany, and University of Groningen, The Netherlands.

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