Abstract

Crystallography is a branch of science that deals with the discerning of the arrangement and bonding of atoms in crystalline solids. Crystal structural differences in the active pharmaceutical ingredient (API)/excipients in multi - source generics of antimal arials may present differences in their physicochemical properties and ultimately the rate and extent of drug absorption. Tackling the menace of the continuing spread of multi - drug resistant Plasmodium falciparum malaria may require the evaluation of the c rystal structural influences of orally administered drugs on antimalarial bioavailability.

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