Crystal and Molecular Structure Studies of a Novel 1-Benzhydryl-piperazine Derivative: 1-Benzhydryl-4-(4-chloro-2-fluoro-benzene-sulfonyl)-piperazine

Abstract

The title compound 1-benzhydryl-4-(4-chloro-2-fluoro-benzenesulfonyl)-piperazine was synthesized, and structure of the product obtained was confirmed by the X-ray diffraction study. The compound C23H22ClFN2O2S crystallizes in the monoclinic crystal class in the space group P21/c with cell parameters a = 9.6180(7) Å , b = 12.9670(10) Å , c = 19.4020(12) Å , β = 114.716(3)°, and Z = 4. The structure has been solved by direct methods and refined to R 1 = 0.0440 for 3877 observed reflections with I > 2σ(I). The structure reveals that the piperazine ring is in a chair conformation. The geometry around the S atom is distorted tetrahedral.