Abstract
Collagen cross-linking (CXL) is the process of formation of covalent bonds within and between the collagen molecules of the corneal stroma. Studies have shown that CXL was able to stabilize keratoconus and postrefractive ectasia for a period of 1–5 years after treatment. The procedure and its technical variations are still controversial. The aim of this study was to present a review on the safety and efficacy of the most commonly used technical variations of CXL.
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