Abstract
Background: Urticaria is recurrent, transient, cutaneous swelling and erythema which resolves within 24 hours without leaving residual cutaneous signs. Approximately 15 to 20% of the general population will have urticaria at least once during their lifetime. Haridrakhanda is one such formulation mentioned in classical text books specially indicated for curing Sheetapitta, Udarda, Kotha etc. A detailed literature survey has been conducted to explore the probable mode of action of Haridrakhanda in Sheetapitta. Most of the ingredients are having Immunomodulatory, antifungal, anti-bacterial, antioxidative and anti-inflammatory activity may work on Sheetapitta. Apart from the ingredients of the formulation are predominant with Katu, Tikta, Kashaya, Madhura Rasa, Ushna Virya, Katu and Madhura Vipaka and Kapha Pitta or Tridosha Shamaka qualities. All the contents of Haridrakhanda are having properties to control the allergic condition and improve Vyadhikshamatva (Immunomodulatory).
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