Abstract

Antimicrobial resistance has been identified as one of the world's most pressing public health threats.The number of antibiotic-resistant bacteria and the diversity of molecular mechanisms of resistance have increased sharply in recent years.The presence of antimicrobial resistance in children complicates patient management and arouses widespread concern.The use of antimicrobial agents is the single most important factor leading to the deve-lopment of resistance.New effective antimicrobial agents has been needed but has not kept pace.Antimicrobial-resis-tant infection can be prevented by immunization as well.Appropriate and judicious use of antimicrobial agents is the most important factors contributing to control resistance.Clinicians should collaborate well with microbiologist and know well about resistant bacteria and its proper antimicrobial drugs.A good application of antibiotic formulary restriction has the potential to decrease antimicrobial resistance.An antimicrobial resistance surveillance between regions and countries is urgently needed.It can help us to understand and slow antimicrobial resistance in the long run. Key words: Pathogenic bacteria; Antibiotics; Antibiotic-resistant; Antimicrobial resistance surveillance

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