Craniofacial osteosarcomas – The challenges in the diagnosis of a biologically distinct entity

Abstract

Osteosarcoma is the second most common primary neoplasm arising from bone next to Multiple myeloma and is common in metaphysis of long bones. Osteosarcoma of the jaw bones is a biologically distinct entity in contrast with Osteosarcoma of the long bones. This review highlights the challenges in the diagnosis of craniofacial osteosarcoma and emphasizes the need for appropriate diagnosis of this entity for proper management.