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Abstract
Tetraalkyl-substituted pyrazines were obtained by the multicomponent reaction of aliphatic linear nitriles with EtAlCl2 in the presence of Mg and Cp2TiCl2 catalyst in 60–91% yields. The same processing of isobutyronitrile gave 2,4,5-triisopropyl-1H-imidazole in 56% yield.
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