Abstract

BackgroundSevere Acute Respiratory Syndrome Coronavirus 2 continues to spread globally and in the absence of an effective treatment, the vaccine remains the best hope for controlling this disease. In this study, we seek to find out the extent to which people in Syria accept the Corona vaccine and what are the factors that affect their decision.MethodsThis cross-sectional study was conducted in Syria during the period from January 3 to March 17, 2021. A structured self-administered questionnaire was distributed in two phases: The first phase included distributing the questionnaire as a Google Form on social media platforms. In the second phase, a paper version of the questionnaire was handed to patients, their companions, and workers in public hospitals. SPSS v.25 and R v.4.1.1 were used to analyze the data. Pearson Chi-square test and Logistic Regression were used to study the associations between categorical groups.ResultsOf 7531 respondents, 3505 (46.5%) were males and 4026 (53.5%) were females. 3124 (41.5%) were 18–24 years old. Healthcare workers were participants’ main sources of information (50.9%), followed by Social Media users (46.3%). 2790 (37%) of the participant are willing to be vaccinated, and 2334 (31%) were uncertain about it. Fear of possible side effects was the main reason for the reluctance to take the vaccine 1615 (62.4%), followed by mistrust of the vaccine formula 1522 (58.8%). 2218 (29.5%) participants think COVID-19 poses a major risk to them personally. Vaccination intention was significantly associated with gender, residence, financial status, educational level, and geographic origin.ConclusionThis study showed very negatively important results. The study participants Vaccination acceptance rate is almost the lowest when compared to its peers. A Lot of efforts should be made to correct misinformation about the vaccine and answer all questions about it, especially with a health system that has been ravaged by war for 10 years.

Highlights

  • Severe Acute Respiratory Syndrome Coronavirus 2 continues to spread globally and in the absence of an effective treatment, the vaccine remains the best hope for controlling this disease

  • Despite applying various preventive measures to minimize the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in the absence of effective treatment, immunization may be presented as the best hope for containing the disease

  • To ensure the correct diversity in the sample and to avoid selection bias, we distributed the questionnaire in two phases: The first phase ran from January 3 to February 1, 2021, in which the questionnaire was distributed as Google Form on social media platforms (Facebook, Whatsapp, and Twitter)

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Summary

Introduction

Severe Acute Respiratory Syndrome Coronavirus 2 continues to spread globally and in the absence of an effective treatment, the vaccine remains the best hope for controlling this disease. Coronavirus disease 2019 (COVID-19) has rapidly become a global threat, affecting (as of December 2019) over 173 million people, causing approximately 4 million deaths, and continuing to affect all aspects of life worldwide [1]. Despite applying various preventive measures to minimize the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in the absence of effective treatment, immunization may be presented as the best hope for containing the disease. The vaccine will play a vital role in reducing infections even among the unvaccinated population, through herd immunity. Based on the current data, (60–75%) of the population should yet acquire the immunity to achieve this endpoint [3]

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