COVID-19 Infection Presenting as Myalgia, Abnormal Liver Function Tests and the Guillain-Barre Syndrome

Senyo Tagboto

doi:10.4236/aid.2022.121011

Abstract

The severe acute respiratory syndrome coronavirus 2 infection typically presents with respiratory symptoms. Additionally, there are a number of less frequent neurological manifestations of infection with the coronavirus disease 2019 (COVID-19) with case reports suggesting an association with the Guillain-Barre syndrome. Most patients present with the typical upper respiratory symptoms in association with these neurological symptoms. We present a case of an unvaccinated gentleman with none of the typical respiratory symptoms of COVID-19 who presented with the Guillain Barre syndrome and myalgia. His symptoms settled following treatment with intravenous immunoglobulins. This case highlights the importance of testing for COVID-19 in patients without typical symptoms but who present with neurological illness and supports the use of intravenous immunoglobulin therapy.

Highlights

Following an outbreak of a contagious lower respiratory tract infection in Wuhan, China at the end of 2019, The World Health Organization (WHO) subsequently declared this a Public Health Emergency of International Concern [1]
There are a number of less frequent neurological manifestations of infection with the coronavirus disease 2019 (COVID-19) with case reports suggesting an association with the Guillain-Barre syndrome
We present a case of an unvaccinated gentleman with none of the typical respiratory symptoms of COVID-19 who presented with the Guillain Barre syndrome and myalgia

Summary

Introduction

Following an outbreak of a contagious lower respiratory tract infection in Wuhan, China at the end of 2019, The World Health Organization (WHO) subsequently declared this a Public Health Emergency of International Concern [1]. This virus was named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and was a novel form of coronavirus belonging to the genus Betacoronavirus and subgenus Sarbecovirus [2]. The Omicron variant is associated with a higher risk of reinfection in previously infected individuals and infection despite prior vaccination. This variant is associated with less severe disease [3] [4]

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Discussion

Conclusion