Cover Picture: Total Synthesis of Paliurine F (Angew. Chem. Int. Ed. 4/2007)

Abstract

The sedative paliurine F, which was isolated from the roots of Paliurus ramossisimus, is part of a huge family of natural products that display interesting biological effects and possess an especially appealing and challenging macrocyclic structure. In their Communication on page 572 ff., G. Evano and co‐workers describe the synthesis of one of these cyclopeptide alkaloids, paliurine F, using a route that showcases the recent advances in copper(I)‐mediated coupling reactions.