Abstract
Abstract The first synthesis of a nine-membered ring by means of an intramolecular Ni(II)/Cr(II)-mediated coupling reaction between an iodoacetylene and an aldehyde is reported. The yield of the reaction is strongly dependent on the substrate concentration, but is independent of both the NiCl2 and CrCl2 concentration at high dilution. The application of this methodology to the synthesis of neocarzinostatin chromophore and other natural products is discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
