Abstract
The cover picture shows a facile and biocompatible approach to generate microgrooves on water-insoluble polymeric surfaces using sugar fibers as the imprinting template. The cover shows a "cotton candy", a favorite food for many children. This time, a research group in Fudan University employed it to serve science, using the sugar fibers in this "cotton" as a sacrificed template to physically modify a biomaterial. The present report is aimed to confirm the feasibility of this idea in the cases of two dimensional films, using poly(lactic-co-glycolic acid) (PLGA) as the model biomaterial matrix. Microgrooves were conveniently generated on PLGA films after removing sugar fibers simply by water. The contact guidance of cells by the microgrooves was confirmed on the resulting surface. More details are discussed in the article by Qu and Ding on page 2292–2296.
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