Cover Picture: C2‐Symmetric Fluorous Diamines and Diimines as Ligands for Metal‐Catalysed Asymmetric Cyclopropanation of Styrene (Eur. J. Org. Chem. 22/2004)

Abstract

AbstractThe cover picture shows a biphasic reaction catalysed by a metal complex of an enantiopure fluorous 1,2‐diamine ligand (L*). C2‐symmetric diamines and diimines bearing perfluoroalkyl ponytails have attracted considerable attention as recoverable chiral ligands in transition‐metal‐catalyzed asymmetric processes. In this case, preformed cobalt(II) and in situ generated copper(I) complexes of such ligands have been tested as catalysts for the cyclopropanation of styrene with diazoacetates. Under optimised reaction conditions, which include the use of a fluorous biphasic system and short reaction times, the copper complex of L* afforded promising results and could be easily separated from the products by simple decantation of the fluorous phase. Details are discussed in the article by G. Pozzi, D. O′Hagan et al. on p. 4545 ff. Cover art by Marco Cavazzini.