Cover Feature: Structural Properties of Hachimoji Nucleic Acids and Their Building Blocks: Comparison of Genetic Systems with Four, Six and Eight Alphabets (ChemPhysChem 5/2023)

Abstract

The Cover Feature illustrates models used to provide detailed structural, conformational, and energetics analysis of the alphabets of hachimoji nucleic acids using an amalgamation of density functional calculations and molecular dynamics simulations. The aim is to explain the experimentally observed stability of hachimoji DNA and RNA. Cover design by Indu Negi and Purshotam Sharma. More information can be found in the Research Article by Purshotam Sharma and co-workers.