Abstract

This study introduces a versatile method for coupling single-stranded DNA with small heterocyclic compounds, leveraging the reactivity of amino and carboxylic functional groups. By employing COMU and Collidine, BNIMZ and BNTZA were successfully coupled with poly-T DNA. The conjugation technique was successfully confirmed by high accuracy MALDI-TOF MS. This approach offers a reliable and efficient strategy for constructing DNA-conjugates with tailored properties.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.