Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?

Abstract

Objective: Elevated blood glucose may be affect complete blood count parameters. In this study, we compared the hemogram parameters of healthy individuals and cases with impaired glucose tolerance.
 Method: We examineted 134 patients with impaired glucose tolerance and 30 healthy cases. Patients files were evaluated retrospectively and the levels of hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, red blood cell, red cell distribution wide, mean platelet volume, platelet distribution wide, leukocycte, neutrophil, lymphocycte, platelet, and hemoglobin A1c were recorded. Control and patient groups were compared in terms of these parameters with student T test. In addition, the relationship between hemoglobin A1c value and complete blood count parameters were determined in patients with impaired glucose tolerance. 
 Results: There was no significantly difference between study and control groups in terms of hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, red blood cell count, red cell distrubition wide, leukocycte, neutrophil, lymphocycte, platelet levels. The mean platelet volume and platelet distribution wide values were significantly higher in the patient group than the control group (p value: 0.002, p value: 0.04 respectively). 
 Conclusion: Complete blood count is an easy, inexpensive test that can be performed in most hospitals. If our study results are supported by other studies, some hemogram parameters may be used to diagnose of impaired glucose tolerance.