COULD EARLY DIAGNOSIS OF METABOLIC SYNDROME LOWER THE INCIDENCE OF ATRIAL FIBRILLATION IN HYPERTENSIVE PATIENTS?: PP.28.123

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Objective: Metabolic syndrome consists of several interrelated risk factors that have been shown to increase the risk of heart disease and also the risk of atrial fibrillation. Method: We have included in the study group patients admitted in Cardiology Center in 2006 and we have divided them in 2 subgroups: individuals with hypertension and metabolic syndrome according to NCEP criteria and the second subgroup of hypertensives without metabolic syndrome. The follow-up period lasted for 3 years. We performed multivariate logistic regression analyses in order to assess the relationships between hypertension, metabolic syndrome, atrial fibrillation, dyslipidemia and diabetes mellitus. Results: We have evaluated 542 patients with metabolic syndrome and hypertension mean age of 55,12 years. There were 48,72% men and 51,28% women. The profile of our MS patients was depicted by older age, higher systolic pressure, higher body mass indexes and higher incidence of atrial fibrillation. The procent of patients with diabetes mellitus was 34,19%, but 27,35% from them had impaired fasting glucose. This population had more left ventricular hypertrophy, renal and cardiac diseases were more prevalent (p < 0.01), and they received more antihypertensive drugs (p < 0.05). Conclusions: The study shows the poor adherence to treatment of hypertensive patients with metabolic syndrome. The hypertensive patients with atrial fibrillation are achieving the target values for blood pressure in a very small percent (p < 0.05). The number of important cardiovascular events is increased in the case of these young patients with a very high risk profile.