Corylus avellana as a potential alternative source for the production of taxol and taxanes

Abstract

This paper demonstrates the increased interest that scientists have recently shown in the non-food components of the hazel plant, such as leaves, as well as hard and green shells, in addition to the nuts. The review discusses studies conducted to determine the qualitative and quantitative profiles of different parts of Corylus avellana. It has been demonstrated that extracts made from various Corylus avellana components possess a variety of biological properties, such as anticancer, antiproliferative, and antioxidant effects. It has been shown that secondary metabolites can be directly synthesized by in vitro cell culture, which allows the production of valuable secondary metabolites such as paclitaxel, one of the most important anticancer compounds synthesized by hazel. A brief review of existing literature data serves to emphasize C.avellana as a source of bioactive compounds. Further research is needed to explore the health benefits of C.avellana extracts and their use as food supplements. Keywords: Hazel, Corylus avellana, secondary metabolites, taxol, anticancer drug