Abstract
The term corticotropin releasing hormone (CRH) was first coined about 40 years ago to describe a hypothalamic derivative that explicitly induces the release of pituitary adrenocorticotropic hormone (ACTH). In 1981, the 41-amino-acid sequence of CRH was characterized by Vale and his colleagues at the Salk Institute. The neuropeptide has satisfied all the requirements as a hypophysiotropic hormone that specifically activates pituitary corticotropes to augment the production of proopiomelanocortin (POMC), the precursor of ACTH, and the release of ACTH.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
