Abstract
A common theme in engineering surfaces for biomedical materials and devices is the control of cell behavior at the material-tissue interface. Multiple analytical techniques are required to fully characterize a material surface both prior to and after exposure to the biological environment. In addition, a full cadre of microscopy techniques are essential for understanding cell behavior to these surface engineered materials. At the heart of understanding the mechanisms that control cell function on solid materials is the adsorption of serum proteins, which ultimately dictates how a cell responds to a material. A great deal of complexity is introduced into the system by adsorbed proteins, since there are over 200 proteins in human blood, and that post adsorption changes in conformation could lead to altered function. Until recently it has been extremely difficult to correlate cell behavior with the initial surface chemistry of a material and the type of protein adsorbed to the surface.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Proceedings, annual meeting, Electron Microscopy Society of America
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
