Abstract
Introduction Multislice computed tomography examinations performed 3 to 4 days after the onset of symptoms is the imaging procedure of choice in acute pancreatitis, which is mainly done for evaluating the complications. Due to radiation exposure and cost, alternative scoring systems like Ranson’s score and Glasgow’s score were devised but were cumbersome. The serum amylase and lipase were found to increase with progression of disease. The objective of this study was to evaluate the association of acute pancreatitis by modified CT scoring system with the serum levels of amylase and lipase. Material and Methods In hundred patients presenting with acute pancreatitis, the severity of pancreatitis was recorded using the modified CT severity index. The serum amylase and lipase levels were recorded and correlated with modified CT severity index score. Results Among 100 patients studied, 46%, 40% and 14% had mild, moderate and severe grades of pancreatitis respectively by modified CTSI score. No significant correlation was found between the levels of serum amylase (r = -0.104, p = 0.301) and lipase (r = -0.177, p = 0.079) with the modified CT severity index in patients with acute pancreatitis. Conclusion The serum level of amylase and lipase had non-significant correlation with the modified CT severity index score and thus did not indicate severity of pancreatitis.
Highlights
Multislice computed tomography examinations performed 3 to 4 days after the onset of symptoms is the imaging procedure of choice in acute pancreatitis, which is mainly done for evaluating the complications
Material and Methods: In hundred patients presenting with acute pancreatitis, the severity of pancreatitis was recorded using the modified CT severity index
No significant correlation was found between the levels of serum amylase (r = -0.104, p = 0.301) and lipase (r = -0.177, p = 0.079) with the modified CT severity index in patients with acute pancreatitis
Summary
Multislice computed tomography examinations performed 3 to 4 days after the onset of symptoms is the imaging procedure of choice in acute pancreatitis, which is mainly done for evaluating the complications. The objective of this study was to evaluate the association of acute pancreatitis by modified CT scoring system with the serum levels of amylase and lipase. Biochemical markers like serum amylase and lipase have been used for diagnosis of acute pancreatitis[AP]. Doing CECT after 48-72 hours of onset of an acute attack, increases the chances of picking the necrotising pancreatitis.[4] The CT imaging features of acute pancreatitis include focal or diffuse enlargement of the pancreas, peripancreatic fat stranding, peripancreatic fascial thickening and fluid collections.[5] CT has an overall accuracy of 87% and sensitivity and specificity of 100% in the detection of pancreatic necrosis.[6,7] Modified CT severity index[ MCTSI] is the most frequently used scoring system used for assessing the severity of acute pancreatitis
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