Correlation of fragmented QRS with right ventricular indexes and fibrosis in patients with repaired tetralogy of fallot, by cardiac magnetic resonance imaging

Abstract

Results The mean percentage of scar tissue in those who had RVEF 45%, that was statistically significant.(P-value= 0.0001). The overall accuracy of the test to identify patients with RVEF 150 ml/m 2 were 87% and 62%, respectively; PPV=70% and NPV=83%.The relation of fQRS and RV end systolic volume index was statistically meaningful. (P-value=0.02)The sensitivity and specificity of fQRS in identifying patients with RVESVI>82 ml/m 2 were 80% and 66%, respectively; PPV=80% and NPV=66%. The relation of mean right ventricular diastolic and systolic diameter with RVEF was statistically considerable according to the P-value=0.0001 and 0.001, respectively; without any meaningful relationship between RV diastolic diameter and fQRS. (P-value=0.1)And there was relationship between RV diastolic diameter and fQRS. (Pvalue=0.014)There was a strong inverse linear relationship between the number of fQRS edges and RVEF (r=0.77, Pvalue=0.0001) in addition to a strong positive linear correlation between the number of edges and the percentage of scar tissue (r=0.88, P-Value=0.001). Conclusions According to this study fQRS could suggest an acceptable screening test in the serial follow up of patients who repaired TOF, considering that CMR was costly and time consuming.