Abstract

Objective To research the correlation of fragmented QRS complex in electrocardiogram (ECG) with ventricular arrhythmia, heart rate variability (HRV) and left ventricular systolic function in patients with acute myocardial infarction (AMI). Methods A total of 120 patients with AMI were selected randomly in the Second Affiliated Hospital of Kunming Medical University from January 2011 to October 2012. There were 99 men and 21 women, aged from 28 to 82 with average age (60±13) years old. Patients were divided into three groups according to the shape of QRS complex in 12-lead ECG: group A (fQRS), group B (pathological Q wave) and group C (fQRS with pathological Q wave). Ventricular arrhythmia and HRV (by dynamic ECG), left ventricular end-diastolic diameter (LVDd) and left ventricular ejection fraction (LVEF) (by Ultrasonic cardiogram) were analyzed and compared among three groups. Results ① The incidence of ventricular arrhythmia (Lown grade III, IVA and IVB) in group A (34.2%, 36.8% and 26.3%)and group C (33.3%, 28.3% and 16.7%) were significantly higher than those in group B (9.1%, 4.5% and 0%), all P<0.05. ②The time domain parameter indicators (SDNN, SDANN index, rMSSD, pNN50, triangular index) of HRV patients in group A, group C were significantly decreased than in group B, all P<0.01.③ LVDD of patients in group A (51.71±8.44 mm) and group C (50.32±7.35 mm) were significantly greater than in group B (45.14±6.44 mm) , and LVEF of patient in group A (46.92%±6.96%)and group C (49.00%±7.80%)were significantly decreased than group B (53.23%±7.95%), all P<0.05. Conclusions fQRS may be related to the reduce of ventricular arrhythmias especially malignant ventricular arrhythmia and HRV, and related to the significant impairment of left ventricular systolic function. Key words: Myocardiol infarction; Arrhythmia, cardiac; Left ventricular systolic function; Fragmented QRS complex

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