Abstract
Dengue infections are currently one of the most rapidly emerging arboviral infections in the world. During this time the emphasis of platelets only limited about number of platelets and very rarely discuss about the quality of platelets (activation and dysfunction). Changes in PDW reflects the activation of platelets. Aim of this study is to analyze the prevalence ratio of PDW enhancement in dengue hemorrhagic fever (DHF) compared to dengue fever (DF). This was a cross-sectional study to analyze the prevalence ratio of enhancement PDW in DHF compared to DF. The subjects were dengue suspected patients who meet the inclusion and exclusion criteria. Venous blood were collected for automatical hematology analysis (include PDW). Different proportions of PDW enhancement between DHF and DF groups was analyzed by Chi-square. One hundred subjects were participated in this study and classified into DF and DHF. Prevalence ratio of PDW enhancement (>64.8%) was 3.1 (95% CI 1.5 – 20.7), p 0.006. The result indicates that PDW enhancement was a risk factor of worsening dengue infection.
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