Abstract
Objectives To summarize the clinical features, imaging features and the selection of microscopic surgical approaches and to investigate the factors of affecting postoperative visual acuity recovery of patients. Methods The clinical data of 44 patients with sellar meningiomas were analyzed retrospectively and the follow-up study was performed. The clinical features, imaging features, and selection of microsurgical approach were summarized. The factors that might affect the recovery of visual acuity in patients after procedure were analyzed respectively with the univariate analysis of non-parametric tests and logistic regression multivariate analysis. Results After univariate analysis, the factors of affecting visual acuity are as follows: duration of preoperative visual impairment (P=0.001), degree of preoperative visual impairment (P=0.001), preoperative fundus change (P=0.001), preoperative visual evoked potential amplitude change (P=0.001), tumor base (P=0.006), tumor texture (P=0.002), tumor growth direction (P=0.003), relationship between tumors and optic nerves (P=0.001), optic nerve morphology in surgery (P=0.001), and relationship between tumors and internal carotid artery and its branches (P=0.038). Multivariate logistic regression analysis found that the degree of preoperative visual impairment (P=0.001), preoperative fundus change (P=0.019), preoperative visual evoked potential amplitude change (P=0.009), and relationship between tumors and optic nerves (P=0.012) were the significant factors for affecting postoperative visual acuity recovery. Conclusions Sellar meningiomas should be diagnosed and treated early. The degree of preoperative visual impairment, preoperative fundus change, preoperative visual evoked potential amplitude change and relationship between tumors and optic nerves are the key factors for affecting postoperative visual acuity recovery. Key words: Meningioma; Sellar region; Visual acuity; Prognosis
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