CORRELATION BETWEEN MYOCARDIAL PERFUSION IMAGING AND CAROTID ULTRA-SONOGRAPHY IN PATIENTS WITH CHEST PAIN

Abstract

Background: Atherosclerosis is a major risk factor for coronary artery disease (CAD). Carotid ultrasound (U/S) may be a useful method for prediction of CAD through measurement of intimio-media thickness (IMT) of right and left common carotic arteries. Objective: To emphasize the correlation between myocardial perfusion imaging using single photon emission computed tomography (SPECT) and carotid ultrasound through measuring IMT in early prediction and diagnosis of CAD. Patients and methods: The study included 80 patients complaining from chest pain. Single photon emission computed tomography (SPECT) and carotid U/S were done to each of them. All Patients were recruited from El-Hussein university hospital outpatient clinic and Kobry El-Koba military hospital outpatient clinic between February 2020 and November 2020. Results: The study included 80 patients, 57 of them were males while 23 of them were females. 52 patients were hypertension (HTN), 31 patients were diabetes mellitus (DM), 33 patients were smokers, 15 patients of them had positive family history. 52 patients had positive SPECT stress test revealing CAD “ischemic group”, while 28 of them had negative SPECT stress test “Non-ischemic group”. For the ischemic group, 43 patients (82.7%) had increased intimio-media thickness IMT. Right IMT mean ± SD “0.69±0.10”, t-test “7.771”, weighted Kappa test 0.655 substantial agreement and P-value “p <0.001”. Lefy IMT mean ± SD “0.77±0.12”, t-test “5.122” , weighted Kappa test 0.614 substantial agreement and p-value “p <0.001”. Only 9 patients (17.3%) from the ischemic group had below 75th percentile IMT. For Non-ischemic group, only 9 patients (32.1%) had abnormal IMT while the other 19 patients (67.9%) had normal IMT. Conclusion: Carotid ultrasound and intimio-media thickness are good predictors and highly correlated to coronary artery disease.