Correlation between level of microalbuminuria and severity of coronary artery disease in coronary heart disease patients combined with diabetes

Abstract

Objective To investigate the correlation between the level of microalbuminuria and severity of coronary artery disease in elderly coronary heart disease(CHD)patients combined with diabetes. Methods A total of 176 elderly CHD patients combined with diabetes were enrolled and prospectively studied.They were randomized into observation group(n=98)with microalbuminuria and the control group(n=78)with normoalbuminuria.The correlation between level of microalbuminuria and Gensini score was analyzed. Results The level of microalbuminuria and Gensini score were higher in observation group than in control group(P<0.05). There were statistically significant differences in level of microalbunminuria(F=9.87, P=0.013)and in Gensini score(F=9.07, P=0.015)among patients with single-, double- and triple-vessel disease.There was a positive correlation between levels of microalbuminuria and Gensini scores in CHD patients with type 2 diabetes(r=0.68, P<0.01). Conclusions The level of microalbuminuria is positively correlated with the severity of coronary artery disease in elderly CHD patients with type 2 diabetes.The microalbuminuria level can reflect the severity of coronary artery disease in a certain degree.It has certain clinical significance for predicting patient's condition in elderly CHD patients with type 2 diabetes. Key words: Coronary artery disease; Diabetes, type 2; Albuminuria