Correlation between Global Longitudinal and Circumferential Peak Systolic Strain and Coronary Artery Disease Severity as Assessed by the Angiographically Derived SYNTAX Score

Abstract

Abstract Aim and objectives the main objective of the current study is to assess the correlation between the SYNTAX score in patients undergoing elective coronary angiography and the longitudinal and circumferential peak systolic strain performed at rest by speckle tracking echocardiography to predict the presence, extent and severity of coronary artery disease. Patients and Methods The study included 60 patients suspected to have coronary artery disease either by symptoms or done a positive non-invasive test for myocardial ischemia with no history of previous ischemia and no previously detected segmental wall motion abnormalities in previous resting echocardiogram. All patients were recruited from the catheter laboratory at the cardiology department of Ain Shams university hospitals and they underwent echocardiographic assessment before elective coronary angiography. Results The study included 60 symptomatic patients suspected to have chronic coronary syndrome aging 31 to 77 years (excluding those with significant structural heart disease). All patients underwent clinical evaluation, surface electrocardiogram, transthoracic echocardiographic, twodimensional speckle tracking, and conventional coronary angiography with SYNTAX score calculation. Patients were divided into 3 groups based on the results of the coronary angiogram: normal CAD on angiogram (n = 12), low SS (n = 28, SS < 22), and high SS (n = 20, SS ≥ 22). Age, sex and most of the risk factors had no statistically significant correlation with the SYNTAX score while There was a significant inverse correlation between GLPSS and GCPSS and SS values (r = 0.458, P = 0.0002), (r = 0.411, P = 0.0011) respectively. Conclusion The results of our study suggest that GLPSS and GCPSS might be promising for the detection of patients with high SYNTAX score on coronary angiogram. There is an inverse correlation between resting GLPSS and GCPSS and SYNTAX score as assessed by coronary angiography.